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Shopping for 2021-Mercedes-Benz-S560
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2021 Mercedes-Benz S560 Oxygen Sensor

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O2 Oxygen SensorO2 Oxygen Sensor
A-Premium®
O2 Oxygen Sensor | 1-Pc Direct-Fit | Heated | A-Premium APOS0540
$33.99
Quantity Less than 2
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3-year warranty
90 days free return
Add Trim and Engine info to ensure a guaranteed fit
Vehicle: 2021 Mercedes-Benz S560
Quantity1
Installation PositionCheck the fitment chart
Item LocatedUnited States
Part interchange
250-241035, 0065422218, 250241035, 2344585, 18086, 234-4585
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O2 Oxygen Sensor
A-Premium®
O2 Oxygen Sensor | 1-Pc Direct-Fit | Heated | A-Premium APOS0371
4.5571 Reviews
$28.99
Edit ZIP code
3-year warranty
90 days free return
Add Trim and Engine info to ensure a guaranteed fit
Vehicle: 2021 Mercedes-Benz S560
Quantity1
Installation PositionCheck the fitment chart
Item LocatedUnited States
Part interchange
250-24253, 25024253, 4727446AD
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2 Pcs O2 Oxygen Sensor
A-Premium®
O2 Oxygen Sensor | 2-Pc Direct-Fit | Heated | A-Premium APOS0400
4.5571 Reviews
$56.99
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3-year warranty
90 days free return
Add Trim and Engine info to ensure a guaranteed fit
Vehicle: 2021 Mercedes-Benz S560
Quantity2
Installation PositionCheck the fitment chart
Item LocatedUnited States
Part interchange
250-24253, 250-24460, 250-24259, 56030100AA, 7B0906265
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AISIN Downstream Oxygen Sensor
Aisin
Downstream O2 Oxygen Sensor | 1-Pc Direct-Fit | Aisin OXSAZ-00747
$43.99
Quantity Less than 4
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3-year warranty
90 days free return
Add Trim and Engine info to ensure a guaranteed fit
Vehicle: 2021 Mercedes-Benz S560
Quantity1
Installation PositionDownstream
Item LocatedUnited States
Part interchange
0065422218, 65422218
ConditionNew
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AISIN 2 Pcs Upstream or Downstream Oxygen Sensor
Aisin
Upstream or Downstream O2 Oxygen Sensor | 2-Pc Direct-Fit | Aisin OXSAZ-00335
$102.99
Edit ZIP code
3-year warranty
90 days free return
Add Trim and Engine info to ensure a guaranteed fit
Vehicle: 2021 Mercedes-Benz S560
Quantity2
Installation PositionUpstream or Downstream
Item LocatedUnited States
Part interchange
25024253
ConditionNew
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Air / Fuel Ratio Sensor - Bosch 17339
Bosch
Air / Fuel Ratio Sensor - Bosch 17339
$122.99
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3-year warranty
90 days free return
Add Trim and Engine info to ensure a guaranteed fit
Vehicle: 2021 Mercedes-Benz S560
Quantity1
Item LocatedUnited States
Part interchange
17339, 0095425518
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Air / Fuel Ratio Sensor - Bosch 17345
Bosch
Air / Fuel Ratio Sensor - Bosch 17345
$121.99
Edit ZIP code
3-year warranty
90 days free return
Add Trim and Engine info to ensure a guaranteed fit
Vehicle: 2021 Mercedes-Benz S560
Quantity1
Item LocatedUnited States
Part interchange
17345, 0095425818
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Air / Fuel Ratio Sensor - Denso 234-5085
Denso
Air / Fuel Ratio Sensor - Denso 234-5085
$167.99
Quantity Less than 2
Edit ZIP code
3-year warranty
90 days free return
Add Trim and Engine info to ensure a guaranteed fit
Vehicle: 2021 Mercedes-Benz S560
Quantity1
Item LocatedUnited States
Part interchange
234-5085, 24330, 009542551864, 0085423018, 0005420700, 009542601864, 0095426218, 0035426918, 
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Walker Products 350-34039 Oxygen Sensor
Walker Products
Walker Products 350-34039 Oxygen Sensor
$41.99
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3-year warranty
90 days free return
Add Trim and Engine info to ensure a guaranteed fit
Vehicle: 2021 Mercedes-Benz S560
Quantity1
Item LocatedUnited States
Part interchange
350-34039
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Walker Products 250-24253 Oxygen Sensor
Walker Products
Walker Products 250-24253 Oxygen Sensor
$67.99
Edit ZIP code
3-year warranty
90 days free return
Add Trim and Engine info to ensure a guaranteed fit
Vehicle: 2021 Mercedes-Benz S560
Quantity1
Item LocatedUnited States
Part interchange
250-24253
Show less
Walker Products 350-35076 Oxygen Sensor
Walker Products
Walker Products 350-35076 Oxygen Sensor
$99.99
Edit ZIP code
3-year warranty
90 days free return
Add Trim and Engine info to ensure a guaranteed fit
Vehicle: 2021 Mercedes-Benz S560
Quantity1
Item LocatedUnited States
Part interchange
350-35076
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Walker Products 350-35034 Oxygen Sensor
Walker Products
Walker Products 350-35034 Oxygen Sensor
$123.99
Edit ZIP code
3-year warranty
90 days free return
Add Trim and Engine info to ensure a guaranteed fit
Vehicle: 2021 Mercedes-Benz S560
Quantity1
Item LocatedUnited States
Part interchange
350-35034
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Walker Products 350-34063 Oxygen Sensor
Walker Products
Walker Products 350-34063 Oxygen Sensor
$107.99
Edit ZIP code
3-year warranty
90 days free return
Add Trim and Engine info to ensure a guaranteed fit
Vehicle: 2021 Mercedes-Benz S560
Quantity1
Item LocatedUnited States
Part interchange
350-34063
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Walker Products 250-25045 Oxygen Sensor
Walker Products
Walker Products 250-25045 Oxygen Sensor
$184.99
Edit ZIP code
3-year warranty
90 days free return
Add Trim and Engine info to ensure a guaranteed fit
Vehicle: 2021 Mercedes-Benz S560
Quantity1
Item LocatedUnited States
Part interchange
250-25045
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Walker Products 250-25042 Oxygen Sensor
Walker Products
Walker Products 250-25042 Oxygen Sensor
$170.99
Edit ZIP code
3-year warranty
90 days free return
Add Trim and Engine info to ensure a guaranteed fit
Vehicle: 2021 Mercedes-Benz S560
Quantity1
Item LocatedUnited States
Part interchange
250-25042
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Walker Products 250-241035 Oxygen Sensor
Walker Products
Walker Products 250-241035 Oxygen Sensor
$127.99
Edit ZIP code
3-year warranty
90 days free return
Add Trim and Engine info to ensure a guaranteed fit
Vehicle: 2021 Mercedes-Benz S560
Quantity1
Item LocatedUnited States
Part interchange
250-241035
Show less

Your vehicle’s oxygen sensor (also known as O2 sensors) plays a critical role in engine performance, fuel efficiency, and emissions control. By continuously measuring the amount of unburned oxygen in the exhaust, the oxygen sensor sends real-time feedback to your engine control unit (ECU), ensuring the perfect air-fuel mixture.

When an oxygen sensor fails, your engine essentially runs “blind,” leading to poor fuel economy, rough idling, reduced performance, and a persistent check engine light. A timely front oxygen sensor replacement or replacement of a faulty upstream oxygen sensor or downstream oxygen sensor can restore optimal driving conditions and help you pass emissions tests with ease.

Why Choose A-Premium Oxygen Sensors?

Unlike universal parts that require cutting and splicing wires, A-Premium O2 sensors are engineered for direct plug-and-play installation.

  • OEM-style connectors for seamless fit
  • Pre-coated anti-seize threads for easy installation
  • Laser-welded body construction for durability
  • High-temperature sintered coating for long service life
  • Premium insulation sheathing and impact-resistant design
  • Slotted guard tube for sensor protection
  • High heat dissipation structure for extreme environments

Advanced Performance & Precision

A-Premium oxygen sensor technology ensures fast, accurate, and stable performance:

Performance & Response

  • ≤200ms fast response time
  • High-efficiency oxygen sensing
  • Zirconia sensing element
  • Real-time signal feedback

Precision & Control

  • Real-time exhaust tracking
  • Accurate combustion control
  • Stable signal output

Efficiency & Engine Benefits

  • Improved fuel efficiency
  • Enhanced engine performance
  • Reduced harmful emissions
  • Extended engine lifespan

Environmental Adaptability

  • Operating range: -40°F to 266°F
  • Air-tight sealing design
  • Stable performance under harsh conditions

3 Symptoms of a Bad Oxygen Sensor

Because O2 sensors operate in extreme heat and carbon-rich environments, they naturally degrade over time.

  • Check Engine Light (CEL): Common codes include P0135, P0171, and P0420. These often point to issues with an upstream oxygen sensor or oxygen sensor bank 1.
  • Poor Fuel Economy: A faulty oxygen sensor may cause a rich fuel mixture, dramatically lowering MPG. 20-40% worse fuel economy overnight.
  • Rough Idle & Stalling: Incorrect readings from your downstream oxygen sensor or upstream sensor can disrupt engine stability.
  • Rotten egg smell: Catalytic converter overheating from bad fuel mixture

Understanding O2 Sensor Positions: Upstream vs Downstream

Modern vehicles may have multiple oxygen sensor units, making it essential to identify the correct one:

  • Oxygen Sensor Bank 1vs Bank 2 
    • oxygen sensor bank 1 refers to the side of the engine with Cylinder #1
    • Bank 2 is the opposite side
  • Upstream Oxygen Sensor(Sensor 1) 
    • Located before the catalytic converter
    • Controls air-fuel ratio
    • Most common need for front oxygen sensor replacement
  • Downstream Oxygen Sensor(Sensor 2) 
    • Located after the catalytic converter
    • Monitors emissions system efficiency

Tip: Always match your diagnostic code to the correct upstream oxygen sensor or downstream oxygen sensor before purchasing.

Complete Your Emissions Repair

Replacing your oxygen sensor is often part of a larger emissions system fix. Consider inspecting these related components:

  • Catalytic Converter: Persistent issues after replacing a downstream oxygen sensor may indicate converter failure
  • MAF Sensor: Works with your oxygen sensor to calculate air intake
  • Ignition Coils & Spark Plugs: Misfires can damage O2 sensors quickly

Shop by Popular Makes

To help you quickly find the right oxygen sensor, explore our most popular vehicle-specific options:

Browse our most searched and best-selling vehicle-specific oxygen sensor options to quickly locate the right fit for your car.